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Health Canada has notified Smart Earth Camelina Corporation that it has no objection to the food use of cold-pressed camelina oil derived from herbicide tolerant camelina line 14CS0851-01-14. The Department conducted a comprehensive assessment of this camelina line according to its Guidelines for the Safety Assessment of Novel Foods. These Guidelines are based upon internationally accepted principles for establishing the safety of foods with novel traits. The safety assessment performed by Food Directorate evaluators was conducted according to Health Canada’s Guidelines for the Safety Assessment of Novel Foods. These Guidelines are based on harmonization efforts with other regulatory authorities and reflects international guidance documents in this area (e.g., Codex Alimentarius). The assessment considered: how herbicide tolerant camelina 14CS0851-01-14 was developed, how the composition and nutritional safety of this variety compared to its unmodified comparator, and what the potential is for this variety to present a toxic or allergenic concern. Smart Earth Camelina Corp. has provided data to support that this variety is safe for use as food in Canada. Health Canada’s review of the information presented in support of the use of thifensulfuron-tolerant camelina line 14CS0851-01-14 does not raise concerns related to food safety.